Dutasteride igurishwa muri farumasi nka Avodart, Avidart, Avolve, Duagen, Dutas, Dutagen, Duprost.Kubwimpamvu zitazwi, ibizamini bya kliniki ya dutasteride byahagaritswe mu buryo butunguranye mu 2002, hanyuma birakomeza nyuma.

Dutasteride ni 5-alpha-reductase inhibitor, bivuze ko ihagarika ibikorwa byimisemburo ya 5a-kugabanya, ishinzwe testosterone ya 5a kugabanya (guhindura) testosterone muri dihydrotestosterone (DHT) hiyongereyeho hydrogene ebyiri.

Dutasteride ibuza isoforms zombi za 5a-reductase, kubwibyo rero birinda ihinduka rya testosterone muri dihydrotestosterone.Ibi bituma Dutasteride ivura neza kubigabo byumugabo.Byumvikane ko, iyo uhinduye Testosterone nkeya muri Dihydrotestosterone, wongera testosterone muburyo budasanzwe (guhinduka gake).

Dutasteride, kuri 2.5mgs / kumunsi ikora hafi 1.5x kurenza Finasteride kuri 5mgs / kumunsi, mugihe cyo kuvura umusatsi (byombi bikabihagarika kimwe no kubisubiramo).Byongeye kandi, Dutasteride irashobora gukoreshwa neza muricyo gipimo kimwe kugirango ivure ubwiyongere bwa prostate, kandi ingaruka itazwi cyane ya Dutasteride (na none, kuri iyo dose imwe) ni ukuvura Acne iterwa no kurenza urugero kwa andorogene mumubiri.

Kuri steroid ukoresheje umukinnyi urwaye ingaruka ziterwa na DHT, Dutasteride irashobora kuba igisubizo.Gukura umusatsi, Acne, na prostate gukura byose (birashoboka) guhagarara rwose hamwe no gukoresha iki gicuruzwa.Kubwamahirwe, DHT ntabwo ari mibi yose, kandi urashobora gutakaza ubukana bwimitsi (ubwiza bwa amorphous niba harigihe buhari), ndetse na zimwe mumico dukunda dukoresha androgene.

Nanone… kubera ko ibi birinda gusa 5a-kugabanya andorogene bitewe no guhinduka muburyo bwa dihydro… birashoboka ko ntacyo bizakora kugirango uhagarike umusatsi cyangwa ibindi bimenyetso biterwa rwose no gukoresha andorogene mumuryango wa DHT.

Dutasteride, hamwe na Finasteride ni 5-alpha-Reductase inhibitor ni itsinda ryibiyobyabwenge bifite anti-androgeneque ibuza ihinduka rya testosterone muri dihydrotestosterone (DHT).Nibintu bimwe biboneka muri Proscar na Propecia kandi bikoreshwa mukuvura hyperplasia na alopecia ya androgene.Kuberako iyi miti igabanya urugero rwa dihydrotestosterone (DHT) ikoreshwa mukurinda no kuvura umusatsi.Bikunze gukoreshwa mukuvura glande nini.