CAS 112809-51-5 Kurwanya Estrogen Steroid Ifu Yera Henlthy Letrozole Femara Kanseri yibere
Byihuse
URUBANZA: 112809-51-5
Synonyme: FEMARA; CGS-20267; LETROZOL; LETROZOLE; LetrozoleUsp28; Letrozole99%; CGS-20267, Femara
Isuku: 99%
Kugaragara: Ibara ryera cyangwa ryerurutse
Inzira ya molekulari: C17H11N5
Uburemere bwa molekuline: 285.31
Ingingo yo gushonga: 181 ° C ~ 183 ° C.
Kurwanya Estrogene Yubaka umubiri Steroide Letrozole Femara Ifu yera CAS 112809-51-5
Ikoreshwa: Ikoreshwa nka API mukuvura indwara yamabere.
Igipimo gisabwa cya Femara nikinini cya mg 2,5 gitangwa rimwe kumunsi, utitaye kumafunguro.
Letrozole igabanya urugero rwa estrogene ku bagore nyuma yo gucura, bishobora kudindiza imikurire yubwoko bumwe na bumwe bwibibyimba byamabere bikenera estrogene kugirango ikure mumubiri.
Letrozole
| ikinini | ibikoresho |
| Garama 1 | Ifu ya Letrozole |
| 19.9 ml | PEG 300 |
| 179.1 ml | 190 Inzoga Yerekana Inzoga |
Letrozole / Gukoresha Femara
Abakoresha muburyo budasanzwe batangaje ko babonye ibisubizo byiza bakoresheje dosiye kuva kuri .25mgs kumunsi kugeza .5mgs kumunsi.Nyamara iyi dosiye iratandukanye cyane kubakoresha kubakoresha, harimo na gahunda yo gukuramo.Bamwe batangaje ko bakoresheje ibice buri munsi cyangwa buri munsi wa gatatu hamwe nibisubizo byiza.Na none, dosiye ivugwa yavuye kuri .25mgs kugeza kuri 2.5mgs kumunsi.
Kubijyanye no kunywa, ugomba guhitamo uhujwe nubuzima bwumubiri wawe, cyangwa ukabaza umutoza wawe / umuganga.Iyi ngingo ireba gusa.
Letrozole / Ingaruka ya Femara
Letrozole mubarwayi ba postmenopausal barwaye kanseri yamabere yateye imbere ya resitora ya Estrogene na / cyangwa progesterone reseptor nziza cyangwa reseptor itazwi
Femara (letrozole) ni ubwoko bwa II (non-steroidal) igisekuru cya gatatu aromatase inhibitor.Mubuvuzi bukoreshwa mukuvura abagore nyuma yo gucura bafite reseptor nziza ya estrogene cyangwa kanseri ya estrogene itazwi.
1. Letrozole ni Inhibitor ikomeye ya Aromatase yakozwe kugirango irwanye kanseri y'ibere.
2. Kubakinnyi nabubaka umubiri, nibiyobyabwenge bikoreshwa mukurwanya ingaruka za estrogeneque ziterwa na anabolike steroid-kubika amazi, acne na gynocomastia.
3. Bizamura kandi testosterone kubera estrogene yagabanutse mumubiri.
4. Femara (izina rusange ni letrozole) ni imiti mishya yatunganijwe mu kuvura kanseri y'ibere yateye imbere ku bagore.
5. Femara niyakabiri mubyiciro bishya byigisekuru cya gatatu guhitamo umunwa wa aromatase inhibitor.
6. Ikora muguhagarika enzyme aromatase, nyuma ikabuza umusaruro wa estrogene.
Letrozole / Femara ibisobanuro
Mu isomo rimwe ryabagabo Letrozole yashoboye kugabanya urugero rwa estrogene kurwego rutamenyekana.Letrozole ishoboye kuzamura testosterone mubigabo.
Letrozole (Femara) ikoreshwa mu kuvura kanseri y'ibere ku bagore batangiye gucura.Letrozole ikunze guhabwa abagore bamaze imyaka 5 bafata tamoxifen (Nolvadex, Soltamox).Letrozole ni inhibitori ya aromatase itari steroidal (igabanya umusaruro wa estrogene).
Letrozole iraboneka muburyo rusange.Ingaruka zisanzwe zirimo gushyuha, guta umusatsi, kubabara / amagufwa / kubabara imitsi, kunanirwa, kubira ibyuya bidasanzwe, isesemi, impiswi, umutwe, hamwe no gusinzira.
Igipimo gisabwa cya Letrozole ni tablet ya mg 2,5 itangwa rimwe kumunsi, utitaye kumafunguro.
Ibindi biyobyabwenge birashobora gukorana na Letrozole.Bwira umuganga wawe ibyanditswe byose hamwe na-imiti-yinyongera ukoresha.Letrozole ntigomba gukoreshwa mugihe utwite.Letrozole irashobora kwangiza akayoya.
Letrozole ikoreshwa cyane cyane kubagore nyuma yo gucura.Niba uherutse guca mu gihe cyo gucura, ganira na muganga kuboneza urubyaro.Ntukoreshe uburyo bwo kuringaniza imbyaro burimo estrogene.Ntibizwi niba Letrozole anyuze mu mashereka kandi bishobora kugirira nabi umwana wonsa.Kugaburira amabere mugihe ukoresha Letrozole ntabwo byemewe.
Letrozole / Femara dosiye ya kanseri y'ibere
1: Ubusanzwe Dose ikuze ya kanseri y'ibere:
Kugira ngo ukoreshwe nk'umurongo wa mbere w'abagore nyuma yo gucura bafite imisemburo ya hormone nziza cyangwa reseptor ya hormone itazwi na kanseri y'ibere yateye imbere cyangwa metastatike.Femara yerekanwa kandi kuvura kanseri yamabere yateye imbere kubagore batangiye gucura bafite uburwayi nyuma yo kuvura antiestrogène: ibinini bya mg 2,5 byatanzwe kumanwa rimwe kumunsi utitaye kumafunguro.
Ku barwayi bafite uburwayi buhanitse, kuvura Letrozole bigomba gukomeza kugeza ibibyimba bigaragaye.
2: Ubusanzwe Dose ikuze ya kanseri y'ibere - Adjuvant:
Kugira ngo ukoreshwe mu buryo bwagutse bwo kuvura kanseri y'ibere hakiri kare ku bagore nyuma yo gucura bakiriye imyaka 5 yo kuvura tamoxifen: ibinini bya mg 2,5 byatanzwe mu kanwa rimwe ku munsi batitaye ku ifunguro.
Igihe cyiza cyo kuvura hamwe na Femara ntabwo kizwi.Ubuvuzi bugomba guhagarikwa niba hari ikibyimba gisubiramo.
Ibicuruzwa birwanya Estrogene
| Kurwanya anti-estrogene | |
| Citrate ya Tamoxifen | URUBANZA No .: 563.64 |
| Citrate Citrate | URUBANZA No .: 50-41-9 |
| Toremifene Citrate | URUBANZA No .: 89778-27-8 |
| Exemestane | URUBANZA No .: 107868-30-4 |
| Anastrozole | URUBANZA No .: 120511-73-1 |
| Letrozole | URUBANZA No .: 112809-51-5 |
| Yuzuye | URUBANZA No .: 129453-61-8 |
